20341
28 Sep 14 at 2 am

(Source: southernsnowdogs, via rydenarmani)

tags: animals  dogs 
 6438
28 Sep 14 at 2 am

okatree:

I remember the day I took this photo, it was probably one of my favourite days of 2013. This hiking trip changed an aspect of me I didn’t know existed.

(via trsom)

tags: nature 
okatree:

I remember the day I took this photo, it was probably one of my favourite days of 2013. This hiking trip changed an aspect of me I didn’t know existed.
 146158
27 Sep 14 at 2 pm
tags: yupp 

lindsaur-gor:

There needs to be a code word or something that means “my brain is fighting me every step of the way today and I feel like I’m going to vibrate out of my skin, so I need you to forgive everything and go slowly and speak softly and lower your expectations.” And then we could all just be like, “I know I said we could go to a movie tonight but… tangerines.” And the other person would nod and squeeze your elbow or rub your head and you wouldn’t feel like a failure.

(Source: krissyboar, via clinicallydepressedpug)

 263756
27 Sep 14 at 4 am

thespectacularspider-girl:

feignedaffections:

allthingshyper:

gehayi:

hiddlesbatchlove:

forever-falling-forward:

platredeparis:

bnycolew:

mannysiege:

Progress

What

Imma just let this sit here

MOTHA FUCKIN SCIENCE

sources:

Engagdget

DailyTech

CBS

They turned RNA into an anti-virus program. That is amazing.

Let me restate this in case it didn’t sink in the first time

Researchers physically DELETED ALL TRACES of the HIV virus from a human cell.

ALL OF IT.

IF YOU ARE NOT EXCITED ABOUT THAT I DON’T THINK YOU KNOW WHAT HIV IS

Here is the original paper.  My computer at work is currently being an ass.
( http://www.hivdent.org/_research_/2014/PNAS-2014-Hu-1405186111.pdf.)

 “Our results also demonstrate, for the first time to our knowledge, that Cas9/gRNA genome editing can be used to immunize cells against HIV-1 infection. The preventative vaccination is independent of HIV-1 strains diversity because the system targets genomic sequences regardless of how the viruses enter the infected cells.”

 “Here, we found that LTR-directed gRNA/  Cas9 eradicates the HIV-1 genome and effectively immunizes target cells against HIV-1 reactivation and infection with high specificity and efficiency. These properties may provide a viable path toward a permanent orsterileHIV-1 cure, and perhaps provide a means to eradicate and vaccinate against other pathogenic viruses.”

This is beyond awesome.  Not only does it cure HIV infection, it immunizes other cells.  They believe it can be applied to other viral infections where the virus integrates into the host’s genome.

Lets think about this for a second.  HIV was first confirmed in 1959, retroactively, by examining the deceased’s preserved blood.  Between 1960 and 1980, HIV and AIDS are both relatively unknown, with many cases only confirmed retroactively by symptoms or studying the deceased years after their death.

In 1980, we have “Patient Zero” in the USA.  This is when HIV/AIDS became publicly known.

1980.  It is now 2014.  34 years.  It took us only 34 years, from widespread knowledge to this first major step in a cure.  34 years.  Just slightly longer than a generation we have fought HIV to this extent.

And we are only going to get better at it. 

(Source: mannysiege, via trilies)

tags: science  hiv  aids 
thespectacularspider-girl:

feignedaffections:

allthingshyper:

gehayi:

hiddlesbatchlove:

forever-falling-forward:

platredeparis:

bnycolew:

mannysiege:

Progress

What

Imma just let this sit here

MOTHA FUCKIN SCIENCE

sources:
Engagdget
DailyTech
CBS

They turned RNA into an anti-virus program. That is amazing.

Let me restate this in case it didn’t sink in the first time
Researchers physically DELETED ALL TRACES of the HIV virus from a human cell.
ALL OF IT.
IF YOU ARE NOT EXCITED ABOUT THAT I DON’T THINK YOU KNOW WHAT HIV IS

Here is the original paper.  My computer at work is currently being an ass.( http://www.hivdent.org/_research_/2014/PNAS-2014-Hu-1405186111.pdf.)
 “Our results also demonstrate, for the first time to our knowledge, that Cas9/gRNA genome editing can be used to immunize cells against HIV-1 infection. The preventative vaccination is independent of HIV-1 strain’s diversity because the system targets genomic sequences regardless of how the viruses enter the infected cells.”
 “Here, we found that LTR-directed gRNA/  Cas9 eradicates the HIV-1 genome and effectively immunizes target cells against HIV-1 reactivation and infection with high specificity and efficiency. These properties may provide a viable path toward a permanent or “sterile” HIV-1 cure, and perhaps provide a means to eradicate and vaccinate against other pathogenic viruses.”
This is beyond awesome.  Not only does it cure HIV infection, it immunizes other cells.  They believe it can be applied to other viral infections where the virus integrates into the host’s genome.

Lets think about this for a second.  HIV was first confirmed in 1959, retroactively, by examining the deceased’s preserved blood.  Between 1960 and 1980, HIV and AIDS are both relatively unknown, with many cases only confirmed retroactively by symptoms or studying the deceased years after their death.
In 1980, we have “Patient Zero” in the USA.  This is when HIV/AIDS became publicly known.
1980.  It is now 2014.  34 years.  It took us only 34 years, from widespread knowledge to this first major step in a cure.  34 years.  Just slightly longer than a generation we have fought HIV to this extent.
And we are only going to get better at it. 
 110198
27 Sep 14 at 4 am

sixpenceee:

A graduate student has created the first man-made biological leaf. It absorbs water and carbon dioxide to produce oxygen just like a plant. He did this by suspending chloroplasts in a mixture made out of silk protein. He believed it can be used for many things but the most striking one is the thought that it could be used for long distance space travel. Plants do not grow in space, but this synthetic material can be used to produce oxygen in a hostile environment. (Video)

(via theunicornkittenkween)

tags: nature  science 
 17094
27 Sep 14 at 2 am

(Source: ammeb, via sara-meow)

tags: nsfw  lingerie 
 296019
27 Sep 14 at 2 am

shannnfayyy:

I HAVE A COOL TAIL WOAH

(Source: gangsterpikachu, via novas-grimoire)

tags: animals  cat 
 3375
27 Sep 14 at 2 am

(Source: noahsiano, via gnostic-forest)

tags: nature 
 5222
27 Sep 14 at 2 am

wombflowers:

gentlerobyn:

Labradorite from Madagascar. Gives me funky dreams when I have it under my pillow at night.

wow!!

(via flow-fairy)

wombflowers:

gentlerobyn:

Labradorite from Madagascar. Gives me funky dreams when I have it under my pillow at night.

wow!!
 15227
21 Sep 14 at 8 pm

(Source: reactionfaces, via ruinedchildhood)

tags: pokemon  same 
 193220
19 Sep 14 at 3 am

klefable:

shockingly, kids are sick and tired of paying hundreds of dollars for overpriced stacks of paper!!!!!! who wouldve thought!!!!!!

(via sugar-nextdoor)

klefable:

shockingly, kids are sick and tired of paying hundreds of dollars for overpriced stacks of paper!!!!!! who wouldve thought!!!!!!
 124269
18 Sep 14 at 2 pm

(Source: saneintolerant, via ruinedchildhood)

tags: same